M
antigen retrieval immunohistochemistry, formalin fixed paraffin embedded, immunohistochemistry protocol, antigen recovery, antigen retrieval buffer, tissue sections, antigen unmasking, antigen retrieval protocol, antigen retrieval pressure cooker, antigen retrieval microwave, antigen retrieval methods, epitope retrieval, antibody, tissue section, immunohistochemistry, paraffin, formalin, citrate buffer, pathology, ihc
A reliable, time tested solution to unmask antigen on formalin-fixed sections
Aptum Biologics Ltd.
38 Baker's Drove
Southampton
SO16 8AD
United Kingdom
References to Retriever
Since the launch or our first Retriever model (in the end of 2003) the four subsequent modifications of this unit were used worldwide in many laboratories. Our current list of publications reporting using Retriever for epitope recovery is over 600 aticles, books, patents and thesis pulications. If yuo would like to review them all, you can download the file with original articles or experiments involving Retriever (known to us, as we all the time find new ones).
Below, for your overview are just a few selected publications, grouped by the journal or by the subject of the research.
Cell & Cell Reports
Chung, K.M., Singh, J., Lawres, L., Dorans, K.J., Garcia, C., Burkhardt, D.B., Robbins, R., Bhutkar, A., Cardone, R., Zhao, X., et al. (2020). Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma. Cell 181, 832-847.e18. 10.1016/j.cell.2020.03.062.
Pagliuca, F.W., Millman, J.R., Gürtler, M., Segel, M., Van Dervort, A., Ryu, J.H., Peterson, Q.P., Greiner, D., and Melton, D.A. (2014). Generation of Functional Human Pancreatic β Cells In Vitro. Cell 159, 428–439. 10.1016/j.cell.2014.09.040.
Rodeheffer, M.S., Birsoy, K., and Friedman, J.M. (2008). Identification of white adipocyte progenitor cells in vivo. Cell 135, 240–249. 10.1016/j.cell.2008.09.036.
Huang, Z., Zhang, Z., Moazzami, Z., Heck, R., Hu, P., Nanda, H., Ren, K., Sun, Z., Bartolomucci, A., Gao, Y., et al. (2022). Brown adipose tissue involution associated with progressive restriction in progenitor competence. Cell Reports 39, 110575. 10.1016/j.celrep.2022.110575.
Mancini, G., Pirruccio, K., Yang, X., Blüher, M., Rodeheffer, M., and Horvath, T.L. (2019). Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight. Cell Reports 26, 2849-2858.e4. 10.1016/j.celrep.2019.02.039.
Zhao, M., Ren, K., Xiong, X., Cheng, M., Zhang, Z., Huang, Z., Han, X., Yang, X., Alejandro, E.U., and Ruan, H.-B. (2020). Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells. Cell Rep 32, 108013. 10.1016/j.celrep.2020.108013.
Other Cell Journals
Zhou, D., Conrad, C., Xia, F., Park, J.-S., Payer, B., Yin, Y., Lauwers, G.Y., Thasler, W., Lee, J.T., Avruch, J., et al. (2009). Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 16, 425–438. 10.1016/j.ccr.2009.09.026.
Peuhu, E., Jacquemet, G., Scheele, C.L.G.J., Isomursu, A., Laisne, M.-C., Koskinen, L.M., Paatero, I., Thol, K., Georgiadou, M., Guzmán, C., et al. (2022). MYO10-filopodia support basement membranes at pre-invasive tumor boundaries. Developmental Cell 57, 2350-2364.e7. 10.1016/j.devcel.2022.09.016
Xu, K., Sacharidou, A., Fu, S., Chong, D.C., Skaug, B., Chen, Z.J., Davis, G.E., and Cleaver, O. (2011). Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling. Dev Cell 20, 526–539. 10.1016/j.devcel.2011.02.010.
Zhao, M., Ren, K., Xiong, X., Xin, Y., Zou, Y., Maynard, J.C., Kim, A., Battist, A.P., Koneripalli, N., Wang, Y., et al. (2022). Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C. Immunity 55, 623-638.e5. 10.1016/j.immuni.2022.03.009.
EMBO Journals
Melkman-Zehavi, T., Oren, R., Kredo-Russo, S., Shapira, T., Mandelbaum, A.D., Rivkin, N., Nir, T., Lennox, K.A., Behlke, M.A., Dor, Y., et al. (2011). miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors. The EMBO Journal 30, 835–845. 10.1038/emboj.2010.361.
Perea, D., Guiu, J., Hudry, B., Konstantinidou, C., Milona, A., Hadjieconomou, D., Carroll, T., Hoyer, N., Natarajan, D., Kallijärvi, J., et al. (2017). Ret receptor tyrosine kinase sustains proliferation and tissue maturation in intestinal epithelia. EMBO J 36, 3029–3045. 10.15252/embj.201696247.
Peuhu, E., Kaukonen, R., Lerche, M., Saari, M., Guzmán, C., Rantakari, P., Franceschi, N.D., Wärri, A., Georgiadou, M., Jacquemet, G., et al. (2016). SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. The EMBO Journal, e201694387. 10.15252/embj.201694387.
Acx, H., Serneels, L., Radaelli, E., Muyldermans, S., Vincke, C., Pepermans, E., Müller, U., Chávez‐Gutiérrez, L., and Strooper, B.D. (2017). Inactivation of γ‐secretases leads to accumulation of substrates and non‐Alzheimer neurodegeneration. EMBO Molecular Medicine 9, 1088–1099. 10.15252/emmm.201707561.
Schumacher, F.-R., Siew, K., Zhang, J., Johnson, C., Wood, N., Cleary, S.E., Al Maskari, R.S., Ferryman, J.T., Hardege, I., Yasmin, et al. (2015). Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia. EMBO Molecular Medicine 7, 1285–1306. 10.15252/emmm.201505444.
Zhao, M., Xiong, X., Ren, K., Xu, B., Cheng, M., Sahu, C., Wu, K., Nie, Y., Huang, Z., Blumberg, R.S., et al. (2018). Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation. EMBO Molecular Medicine, e8736. 10.15252/emmm.201708736.
Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease (2022). EMBO reports 23, e54271. 10.15252/embr.202154271.
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
Antigen retriever, immunohistochemistry, tissue sections, antigen recovery, formalin-fixed, paraffin embedded tissue sections, immunohistochemistry protocols
écupération d'antigène, 抗原检索
antigen vyhledávání,
antigen hentning,antigen herstel,
antigeeni otsing, antigeeni haku
ανάκτηση αντιγόνου
אנטיגן אחזור
antigene recupero
항원 검색
antigenas paieška
antigen gjenfinning
بازیابی آنتی ژن
مستضد استرجاع
odzyskiwanie antigen
recuperação antigênica
antigen de regăsire
антигена преузимање
antígeno de recuperación de
antigenåtervinning
antijen alımı
مائجن بازیافت
paraffin immunohistochemistry
البارافين المناعية
石蜡免疫组化
parafín imunohistochemie
paraffin immunhistokemi
paraffine immunohistochemie
parafiini immunohistokemiallisesti
immunohistochimie paraffine
Paraffin Immunhistochemie
פרפין אימונוהיסטוכימיה
paraffina immunoistochimica
ανοσοϊστοχημεία παραφίνη
パラフィン免疫組織化学
imunohistoquímica parafina
парафин иммуногистохимия
inmunohistoquímica de parafina
parafin immünhistokimya
paraffin immunohistokemi
Journals:
Area of Reserch:
Nature & Nat.Communications, Nat .Medicine, Nat. Cell Biology
Perera, R.M., Stoykova, S., Nicolay, B.N., Ross, K.N., Fitamant, J., Boukhali, M., Lengrand, J., Deshpande, V., Selig, M.K., Ferrone, C.R., et al. (2015). Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 524, 361–365. 10.1038/nature14587.
Saha, S.K., Parachoniak, C.A., Ghanta, K.S., Fitamant, J., Ross, K.N., Najem, M.S., Gurumurthy, S., Akbay, E.A., Sia, D., Cornella, H., et al. (2014). Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature 513, 110–114. 10.1038/nature13441.
Almstedt, E., Elgendy, R., Hekmati, N., Rosén, E., Wärn, C., Olsen, T.K., Dyberg, C., Doroszko, M., Larsson, I., Sundström, A., et al. (2020). Integrative discovery of treatments for high-risk neuroblastoma. Nature Communications 11, 71. 10.1038/s41467-019-13817-8.
Apóstolo, N., Smukowski, S.N., Vanderlinden, J., Condomitti, G., Rybakin, V., ten Bos, J., Trobiani, L., Portegies, S., Vennekens, K.M., Gounko, N.V., et al. (2020). Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nature Communications 11, 5171. 10.1038/s41467-020-18956-x.
Astanina, E., Doronzo, G., Corà, D., Neri, F., Oliviero, S., Genova, T., Mussano, F., Middonti, E., Vallariello, E., Cencioni, C., et al. (2022). The TFEB-TGIF1 axis regulates EMT in mouse epicardial cells. Nat Commun 13, 5191. 10.1038/s41467-022-32855-3.
Everard, A., Geurts, L., Caesar, R., Hul, M.V., Matamoros, S., Duparc, T., Denis, R.G.P., Cochez, P., Pierard, F., Castel, J., et al. (2014). Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status. Nature Communications 5, 5648. 10.1038/ncomms6648.
Kaukonen, R., Mai, A., Georgiadou, M., Saari, M., De Franceschi, N., Betz, T., Sihto, H., Ventelä, S., Elo, L., Jokitalo, E., et al. (2016). Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun 7. 10.1038/ncomms12237.
Pietilä, M., Sahgal, P., Peuhu, E., Jäntti, N.Z., Paatero, I., Närvä, E., Al-Akhrass, H., Lilja, J., Georgiadou, M., Andersen, O.M., et al. (2019). SORLA regulates endosomal trafficking and oncogenic fitness of HER2. Nature Communications 10, 2340. 10.1038/s41467-019-10275-0.
Seishima, R., Leung, C., Yada, S., Murad, K.B.A., Tan, L.T., Hajamohideen, A., Tan, S.H., Itoh, H., Murakami, K., Ishida, Y., et al. (2019). Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development. Nature Communications 10, 5378. 10.1038/s41467-019-13363-3.
Adriaens, C., Standaert, L., Barra, J., Latil, M., Verfaillie, A., Kalev, P., Boeckx, B., Wijnhoven, P.W.G., Radaelli, E., Vermi, W., et al. (2016). p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med 22, 861–868. 10.1038/nm.4135.
Adriaens, C., Standaert, L., Barra, J., Latil, M., Verfaillie, A., Kalev, P., Boeckx, B., Wijnhoven, P.W.G., Radaelli, E., Vermi, W., et al. (2016). p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med 22, 861–868. 10.1038/nm.4135.
Lopez, R.G., Garcia-Silva, S., Moore, S.J., Bereshchenko, O., Martinez-Cruz, A.B., Ermakova, O., Kurz, E., Paramio, J.M., and Nerlov, C. (2009). C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat. Cell Biol. 11, 1181–1190. 10.1038/ncb1960.
Nittner, D., Lambertz, I., Clermont, F., Mestdagh, P., Köhler, C., Nielsen, S.J., Jochemsen, A., Speleman, F., Vandesompele, J., Dyer, M.A., et al. (2012). Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation. Nat Cell Biol 14, 958–965. 10.1038/ncb2556.
PNAS
Gao, X., Vockley, C.M., Pauli, F., Newberry, K.M., Xue, Y., Randell, S.H., Reddy, T.E., and Hogan, B.L.M. (2013). Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium. PNAS 110, 9356–9361. 10.1073/pnas.1307589110
.
Lee, J.J., Perera, R.M., Wang, H., Wu, D.-C., Liu, X.S., Han, S., Fitamant, J., Jones, P.D., Ghanta, K.S., Kawano, S., et al. (2014). Stromal response to Hedgehog signaling restrains pancreatic cancer progression. PNAS 111, E3091–E3100. 10.1073/pnas.1411679111.
Zhang, H., Pasolli, H.A., and Fuchs, E. (2011). Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. PNAS 108, 2270–2275. 10.1073/pnas.1019603108.
Zhao, Y., Kwan, K.-M., Mailloux, C.M., Lee, W.-K., Grinberg, A., Wurst, W., Behringer, R.R., and Westphal, H. (2007). LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. PNAS 104, 13182–13186. 10.1073/pnas.0705464104.
Rock, J.R., Barkauskas, C.E., Cronce, M.J., Xue, Y., Harris, J.R., Liang, J., Noble, P.W., and Hogan, B.L.M. (2011). Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition. Proc. Natl. Acad. Sci. U.S.A. 108, E1475-1483. 10.1073/pnas.1117988108.
Svensson, M.N.D., Andersson, K.M.E., Wasén, C., Erlandsson, M.C., Nurkkala-Karlsson, M., Jonsson, I.-M., Brisslert, M., Bemark, M., and Bokarewa, M.I. (2015). Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination. Proc Natl Acad Sci U S A 112, E6644–E6653. 10.1073/pnas.1514191112.
Journal Of Experimental Medicine
Janardhan, H.P., Meng, X., Dresser, K., Hutchinson, L., and Trivedi, C.M. (2020). KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K–MAPK1 inhibition. Journal of Experimental Medicine 217. 10.1084/jem.20192205.
Luo, M., Flood, E.C., Almeida, D., Yan, L., Berlin, D.A., Heerdt, P.M., and Hajjar, K.A. (2017). Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. Journal of Experimental Medicine 214, 2535–2545. 10.1084/jem.20160652.
Cell Biology
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Chung, K.M., Singh, J., Lawres, L., Dorans, K.J., Garcia, C., Burkhardt, D.B., Robbins, R., Bhutkar, A., Cardone, R., Zhao, X., et al. (2020). Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma. Cell 181, 832-847.e18. 10.1016/j.cell.2020.03.062.
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Pagliuca, F.W., Millman, J.R., Gürtler, M., Segel, M., Van Dervort, A., Ryu, J.H., Peterson, Q.P., Greiner, D., and Melton, D.A. (2014). Generation of Functional Human Pancreatic β Cells In Vitro. Cell 159, 428–439. 10.1016/j.cell.2014.09.040.
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Rodeheffer, M.S., Birsoy, K., and Friedman, J.M. (2008). Identification of white adipocyte progenitor cells in vivo. Cell 135, 240–249. 10.1016/j.cell.2008.09.036.
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Ghahremani, M.F., Radaelli, E., Haigh, K., Bartunkova, S., Haenebalcke, L., Marine, J.-C., Goossens, S., and Haigh, J.J. (2014). Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice. Cell Cycle 13, 1501–1507. 10.4161/cc.28474.
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Fouchécourt, S., Livera, G., Messiaen, S., Fumel, B., Parent, A.-S., Marine, J.-C., and Monget, P. (2016). Apoptosis of Sertoli cells after conditional ablation of murine double minute 2 (Mdm2) gene is p53-dependent and results in male sterility. Cell Death Differ 23, 521–530. 10.1038/cdd.2015.120.
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Liu, C., Zhang, C.-W., Zhou, Y., Wong, W.Q., Lee, L.C., Ong, W.Y., Yoon, S.O., Hong, W., Fu, X.-Y., Soong, T.W., et al. (2018). APP upregulation contributes to retinal ganglion cell degeneration via JNK3. Cell Death & Differentiation 25, 661–676. 10.1038/s41418-017-0005-3.
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Rabachini, T., Fernandez-Marrero, Y., Montani, M., Loforese, G., Sladky, V., He, Z., Bachmann, D., Wicki, S., Villunger, A., Stroka, D., et al. (2017). BOK promotes chemical-induced hepatocarcinogenesis in mice. Cell Death & Differentiation, 1. 10.1038/s41418-017-0008-0.
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Tan, M.W.Y., Sng, M.K., Cheng, H.S., Low, Z.S., Leong, B.J.J., Chua, D., Tan, E.H.P., Chan, J.S.K., Yip, Y.S., Lee, Y.H., et al. (2020). Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice. Cell Death & Differentiation 27, 2668–2680. 10.1038/s41418-020-0535-y.
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Messenger, Z.J., Hall, J.R., Jima, D.D., House, J.S., Tam, H.W., Tokarz, D.A., and Smart, R.C. (2018). C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis 9, 1–16. 10.1038/s41419-018-1103-y.
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Roach, E.E., Chakrabarti, R., Park, N.I., Keats, E.C., Yip, J., Chan, N.G., and Khan, Z.A. (2012). Intrinsic regulation of hemangioma involution by platelet-derived growth factor. Cell Death Dis 3, e328. 10.1038/cddis.2012.58.
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Yalcin, A., Clem, B.F., Imbert-Fernandez, Y., Ozcan, S.C., Peker, S., O’Neal, J., Klarer, A.C., Clem, A.L., Telang, S., and Chesney, J. (2014). 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27. Cell Death Dis 5, e1337. 10.1038/cddis.2014.292.
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Shan, B., Barker, C.S., Shao, M., Zhang, Q., Gupta, R.K., and Wu, Y. (2022). Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity. Cell Metabolism 34, 783-799.e7. 10.1016/j.cmet.2022.03.012.
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Shao, M., Ishibashi, J., Kusminski, C.M., Wang, Q.A., Hepler, C., Vishvanath, L., MacPherson, K.A., Spurgin, S.B., Sun, K., Holland, W.L., et al. (2016). Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program. Cell Metab 23, 1167–1184. 10.1016/j.cmet.2016.04.023.
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Yue, S., Li, J., Lee, S.-Y., Lee, H.J., Shao, T., Song, B., Cheng, L., Masterson, T.A., Liu, X., Ratliff, T.L., et al. (2014). Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness. Cell Metabolism 19, 393–406. 10.1016/j.cmet.2014.01.019.
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Huang, Z., Zhang, Z., Moazzami, Z., Heck, R., Hu, P., Nanda, H., Ren, K., Sun, Z., Bartolomucci, A., Gao, Y., et al. (2022). Brown adipose tissue involution associated with progressive restriction in progenitor competence. Cell Reports 39, 110575. 10.1016/j.celrep.2022.110575.
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Mancini, G., Pirruccio, K., Yang, X., Blüher, M., Rodeheffer, M., and Horvath, T.L. (2019). Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight. Cell Reports 26, 2849-2858.e4. 10.1016/j.celrep.2019.02.039.
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Zhao, M., Ren, K., Xiong, X., Cheng, M., Zhang, Z., Huang, Z., Han, X., Yang, X., Alejandro, E.U., and Ruan, H.-B. (2020). Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells. Cell Rep 32, 108013. 10.1016/j.celrep.2020.108013.
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Atiakshin, D., Samoilova, V., Buchwalow, I., and Tiemann, M. (2021). Expression of CD38 in Mast Cells: Cytological and Histotopographic Features. Cells 10, 2511. 10.3390/cells10102511.
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Harms, J.K., Lee, T.-W., Wang, T., Lai, A., Kee, D., Chaplin, J.M., McIvor, N.P., Hunter, F.W., Macann, A.M.J., Wilson, W.R., et al. (2019). Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models. Cells 8, 717. 10.3390/cells8070717.
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Huwart, S.J.P., de Wouters d’Oplinter, A., Rastelli, M., Van Hul, M., de Vos, W.M., Luquet, S., Cani, P.D., and Everard, A. (2022). Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of Akkermansia muciniphila. Cells 11, 2534. 10.3390/cells11162534.
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Lopez, R.G., Garcia-Silva, S., Moore, S.J., Bereshchenko, O., Martinez-Cruz, A.B., Ermakova, O., Kurz, E., Paramio, J.M., and Nerlov, C. (2009). C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat. Cell Biol. 11, 1181–1190. 10.1038/ncb1960.
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Nittner, D., Lambertz, I., Clermont, F., Mestdagh, P., Köhler, C., Nielsen, S.J., Jochemsen, A., Speleman, F., Vandesompele, J., Dyer, M.A., et al. (2012). Synthetic lethality between Rb, p53 and Dicer or miR-17–92 in retinal progenitors suppresses retinoblastoma formation. Nat Cell Biol 14, 958–965. 10.1038/ncb2556.
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Jamora, C., Lee, P., Kocieniewski, P., Azhar, M., Hosokawa, R., Chai, Y., and Fuchs, E. (2004). A Signaling Pathway Involving TGF-β2 and Snail in Hair Follicle Morphogenesis. PLoS Biol 3, e11. 10.1371/journal.pbio.0030011.
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Akhlaghpour, A., Taei, A., Ghadami, S.A., Bahadori, Z., Yakhkeshi, S., Molamohammadi, S., Kiani, T., Samadian, A., Ghezelayagh, Z., Haghparast, N., et al. (2020). Chicken Interspecies Chimerism Unveils Human Pluripotency. Stem Cell Reports. 10.1016/j.stemcr.2020.11.014.
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Anderson, A.J., Piltti, K.M., Hooshmand, M.J., Nishi, R.A., and Cummings, B.J. (2017). Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury. Stem Cell Reports 8, 249–263. 10.1016/j.stemcr.2016.12.018.
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Chin, A.M., Tsai, Y.-H., Finkbeiner, S.R., Nagy, M.S., Walker, E.M., Ethen, N.J., Williams, B.O., Battle, M.A., and Spence, J.R. (2016). A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells. Stem Cell Reports 7, 826–839. 10.1016/j.stemcr.2016.09.004.
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Murphy, M.M., Keefe, A.C., Lawson, J.A., Flygare, S.D., Yandell, M., and Kardon, G. (2014). Transiently Active Wnt/β-Catenin Signaling Is Not Required but Must Be Silenced for Stem Cell Function during Muscle Regeneration. Stem Cell Reports 3, 475–488. 10.1016/j.stemcr.2014.06.019.
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Robert, T., De Mesmaeker, I., Stangé, G.M., Suenens, K.G., Ling, Z., Kroon, E.J., and Pipeleers, D.G. (2018). Functional Beta Cell Mass from Device-Encapsulated hESC-Derived Pancreatic Endoderm Achieving Metabolic Control. Stem Cell Reports 10, 739–750. 10.1016/j.stemcr.2018.01.040.
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Sontag, C.J., Uchida, N., Cummings, B.J., and Anderson, A.J. (2014). Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem Cells. Stem Cell Reports 2, 620–632. 10.1016/j.stemcr.2014.03.005.
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Developmental Biology
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Mathew, S.J., Hansen, J.M., Merrell, A.J., Murphy, M.M., Lawson, J.A., Hutcheson, D.A., Hansen, M.S., Angus-Hill, M., and Kardon, G. (2011). Connective tissue fibroblasts and Tcf4 regulate myogenesis. Development 138, 371–384. 10.1242/dev.057463.
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Virology & Microbiology
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Adetunji, S.A., Faustman, D.L., Adams, L.G., Garcia-Gonzalez, D.G., Hensel, M.E., Khalaf, O.H., and Arenas-Gamboa, A.M. (2020). Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization. Infection and Immunity 88. 10.1128/IAI.00257-20.
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Haley, N.J., Mathiason, C.K., Carver, S., Telling, G.C., Zabel, M.D., and Hoover, E.A. (2012). Sensitivity of protein misfolding cyclic amplification versus immunohistochemistry in ante-mortem detection of chronic wasting disease. Journal of General Virology 93, 1141–1150. 10.1099/vir.0.039073-0.
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Immunology & Leukocyte Biology
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Neuroscience
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Fu, Y., He, Y., Phan, K., Bhatia, S., Pickford, R., Wu, P., Dzamko, N., Halliday, G.M., and Kim, W.S. (2022). Increased unsaturated lipids underlie lipid peroxidation in synucleinopathy brain. Acta Neuropathologica Communications 10, 165. 10.1186/s40478-022-01469-7.
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Lehmann, M., Marklund, M., Bolender, A.-L., Bidhendi, E.E., Zetterström, P., Andersen, P.M., Brännström, T., Marklund, S.L., Gilthorpe, J.D., and Nordström, U. (2020). Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in SOD1 ALS model mice. Acta Neuropathologica Communications 8, 161. 10.1186/s40478-020-01032-2.
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Murray, H.C., Dieriks, B.V., Swanson, M.E.V., Anekal, P.V., Turner, C., Faull, R.L.M., Belluscio, L., Koretsky, A., and Curtis, M.A. (2020). The unfolded protein response is activated in the olfactory system in Alzheimer’s disease. Acta Neuropathologica Communications 8, 109. 10.1186/s40478-020-00986-7.
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Davidson, J.O., Draghi, V., Whitham, S., Dhillon, S.K., Wassink, G., Bennet, L., and Gunn, A.J. (2018). How long is sufficient for optimal neuroprotection with cerebral cooling after ischemia in fetal sheep? J Cereb Blood Flow Metab 38, 1047–1059. 10.1177/0271678X17707671.
Cancer Research
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Honeth, G., Bendahl, P.-O., Ringnér, M., Saal, L.H., Gruvberger-Saal, S.K., Lövgren, K., Grabau, D., Fernö, M., Borg, Å., and Hegardt, C. (2008). The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Research 10, R53. 10.1186/bcr2108.
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Chakroborty, D., Goswami, S., Fan, H., Frankel, W.L., Basu, S., and Sarkar, C. (2022). Neuropeptide Y, a paracrine factor secreted by cancer cells, is an independent regulator of angiogenesis in colon cancer. Br J Cancer 127, 1440–1449. 10.1038/s41416-022-01916-1.
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Mao, X., McManaway, S., Jaiswal, J.K., Hong, C.R., Wilson, W.R., and Hicks, K.O. (2019). Schedule-dependent potentiation of chemotherapy drugs by the hypoxia-activated prodrug SN30000. Cancer Biology & Therapy 20, 1258–1269. 10.1080/15384047.2019.1617570.
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Hoffmann, D., Dvorakova, T., Stroobant, V., Bouzin, C., Daumerie, A., Solvay, M., Klaessens, S., Letellier, M.-C., Renauld, J.-C., Baren, N. van, et al. (2020). Tryptophan 2,3-Dioxygenase Expression Identified in Human Hepatocellular Carcinoma Cells and in Intratumoral Pericytes of Most Cancers. Cancer Immunol Res 8, 19–31. 10.1158/2326-6066.CIR-19-0040.
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